Tuesday, May 29, 2007

Die casting defects

Die casting software

Advantages of dieCAS® Software
Unlike other general purpose casting analysis products, dieCAS® software is specialized to die casting. As a result, it can take advantage of die casting’s characteristics and achieve enormous savings in analysis time, without sacrificing solution accuracy.

The analysis is based on a shell-like finite element model of the casting together with a three-dimensional finite element model of the die. This combination creates the following unique advantages:

Direct Calculation of the Steady Periodic Die Temperatures. Unlike all other commercial systems, dieCAS® software does not have to analyze the leading process transient to calculate die temperatures at steady state. This reduces computer time from several days (and even weeks for a large die) to a few hours.

Simplified Model Creation & Editing. Because dieCAS® uses three-dimensional unstructured finite element meshes automatically, the user has to generate only the surface mesh to create the volume mesh automatically. This simplifies the process of both creating and editing the die model. Since cooling lines are represented by one-dimensional elements in the die interior, they can be altered independently of the die model.

Rapid Analysis of Cavity Fill. The unique two-dimensional representation of the die cavity enables an extremely fast analysis of liquid metal flow during cavity fill. Cavity fill run times for even large castings are just a few hours, compared with several days for conventional methods.

Complete Thermo-Mechanical Model of Casting and Die Distortion. Thermal distortions and residual stresses are calculated with minimal user input after the completion of filling and thermal analyses. All Results are available in about an hour, even on very large dies

Tuesday, May 22, 2007

Spray Drying Process

Spray Drying Process
Computer-aided Engineering (CAE) in process modeling and equipment design has become an important factor for Pharmaceutical applications and Process Analytical Technology (PAT). CAE complements existing testing methods by reducing costs and improving quality. CAE can also be used for scale-up studies.

Some Objectives of Using CAE for Spray Drying Process
Identify system and process parameters to maximize residence time of droplets/particles
Predict temperatures and phase change of product to ensure product stability

Some Benefits of Using CAE
Minimize cost of testing to optimize design and process conditions
Increase yield and minimize loss of product due to "glassing"
"What if" scenarios can be tried for day-to-day operations, as well as design optimization

Since 1985, Technalysis has been providing CAE engineering services and software and accumulated considerable experience using CAE for Pharmaceutical, Chemical and Food process modeling and equipment design. Please contact us to discuss your needs.

Fermentation technology

Fermentation technology
Computer-aided Engineering (CAE) in process modeling and equipment design has become an important factor for Pharmaceutical applications and Process Analytical Technology (PAT). CAE complements existing testing methods by reducing costs and improving quality. CAE can also be used for scale-up studies. Since 1985, Technalysis has been providing CAE engineering services and software and accumulated considerable experience using CAE for Pharmaceutical, Chemical and Food process modeling and equipment design. Please contact us to discuss your needs.Technalysis' Passage Software already have many application areas for Pharmaceutical application. However, Technalysis can customize its Passage Software based on specific application.

Some Objectives of Using CAE for Fermentation Tank Design
Simulate fluid mixing and heat transfer
Determine influence of cone angle on fluid mixing and temperature distribution
Locate temperature sensors for accurate process control ...more on using CAE for fermentation technology

Monday, May 21, 2007

Process Analytical Technologies (PAT)

Phase Technologies, Inc.
Phase Technologies, Inc. is an organization that is dedicated to applying the Process Analytical Technologies (PAT) guidelines to the lyophilizationand the freeze-drying processes that are used in the manufacture of pharmaceutical, biotechnology, and diagnostic products. The application of PAT Guidelines to lyophilization and freeze drying requires that the processes be based on science rather than art. Use the links on this page to learn more about how the instrumentation, equipment, technical information, educational programs and services that we offer can bring the PAT guidelines to the lyophilization and freeze drying processes. The following provides you with an easy to use web map of this site.

Process Analytical Technologies (PAT)
Moisture in Elastomer Closures -
Closure Moisture Analyzer (CMA) A rapid (1 sec.) and non-destructive instrument for monitoring the moisture in closures.
Publications - Papers and publications pertaining to PAT and moisture in closures
PowerPoint Presentations - PowerPoint Presentations on PAT and moisture in closure... more at http://www.phase-technologies.com/

Tuesday, May 08, 2007

Casting Simulation Software

Casting Simulation Software - Engineering Services - PASSAGE®/PowerCAST by Technalysis

Overview
PASSAGE®/PowerCAST casting simulation software is a 3-D Finite Element program for predicting the manufacturability of cast parts.

Discrete Element Modeling

Discrete Element Modeling - Passage DEM Software- Passage Discrete Element Method (DEM) Software

Overview :
PASSAGE® Discrete Element Method (DEM) Software is for predicting the flow particles under a wide variety of forces. It can be used alone or together with our PASSAGE®/FLOW Software.


Some Application Areas
Computers Printers
Pharmaceutical
Processes Food
Processing Material
Processing Mixing
Problems
Custom software

Process and Analytical Technology  (PAT) Initiative

Process and Analytical Technology (PAT) Initiative

Process Analytical Technology is:
a system for designing, analyzing, and controlling manufacturing through timely measurements (i.e., during processing) of critical quality and performance attributes of raw and in-process materials and processes with the goal of ensuring final product quality.
It is important to note that the term analytical in PAT is viewed broadly to include chemical, physical, microbiological, mathematical, and risk analysis conducted in an integrated manner.

Process Analytical Technology tools:
There are many current and new tools available that enable scientific, risk-managed pharmaceutical development, manufacture, and quality assurance. These tools, when used within a system can provide effective and efficient means for acquiring information to facilitate process understanding, develop risk-mitigation strategies, achieve continuous improvement, and share information and knowledge. In the PAT framework, these tools can be categorized as:
Multivariate data acquisition and analysis tools
Modern process analyzers or process analytical chemistry tools
Process and endpoint monitoring and control tools
Continuous improvement and knowledge management tools
An appropriate combination of some, or all, of these tools may be applicable to a single-unit operation, or to an entire manufacturing process and its quality assurance. more....Process and Analytical Technology (PAT) Initiative

Related CAE resources by Technalysis, Inc.
CFD consulting and CFD software - flow modeling, freeze drying, powder mixing...

Wednesday, May 02, 2007

Process Analytical Technology (PAT) - Chromatography

CFD Process Modeling Software for Pharmaceutical and Chemical IndustryTechnalysis has been providing advanced CAE technology to the pharmaceutical and chemical companies and its suppliers with its Technalysis® Engineering and Passage® Software within wide range of application areas... http://technalysis.us/pharmaceutical_industry.aspx